I've tried the Acetyl-L-Carnitine on two separate occasions. On the first occasion, I used it for approximately 8 weeks and didn't notice any difference. It's possible that this wasn't long enough for the impact to be felt. More recently, I've been on it as well as many of the "sticky" vitamins. I have had reductions in headache pain, but this is most likely due to a recent increase in Cymbalta to 120 mg from 60 mg.

Not sure this is overly helpful. From the literature, though, this supplement looks promising.