soccertese,

I'm 10 years post diagnosis and doing fairly well in spite of very bad constipation and emerging dystonia. For instance, last week I did an 18 mile walk, which I would have found easy were it not for a painful lean to the left that developed during the day.

For the last 5 years I've been on Stalevo, 75mg four times per day, ropinirole controlled release 16mg once per day (though I'm currently trying it at 8mg twice per day), rasagiline (1mg per day).

Sometimes I get the brand name Requip XL, sometimes the generic Ralnea XL. I haven't done any detailed measurement of their relative effect, but subjectively I can't tell any difference between them.

The rasagiline has no obvious effect on me. This is consistent:
- either with a low but continuous impact totalling the equivalent of 100mg over a day;
- or with it having no effect.
I've not done the experiment to determine which of the cases it is.

John