both are autoimmune. When this happens, it could be an expression
of Gluten intolerance.(autoimmune reactions to the peptides in wheat, barley, and rye)...so check our Gluten forum here too.

Hypothyroidism causes the hands to get this way (carpal tunnel). I had that
severely with my pregnancy.

If she tests positive for carpal tunnel there are injections often given for
that. And during the night using the typical carpal tunnel braces (sold in drug stores) will help prevent the discomfort. I found that just using the night
braces, helped my hands all day (I didn't need them then).

Sometimes low blood sugar causes hand tingling. But so does Raynaud's, and other autoimmune disease like Scleroderma. Diabetics can get pretty hypoglycemic during the night. There are snack bars called Glucerna made especially for this, to keep blood sugar more stable during the night.
She should test immediately upon awakening with her glucometer, to see
if she is low in the morning..before any food is eaten or insulin injected.

A simple thing right now that can do no harm is to get the Carpal Tunnel wrist splints and wear them to bed.