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Old 08-27-2015, 10:54 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Yes, this topical approach avoids the magnesium warning on gabapentin. Magnesium orally complexes gabapentin in the stomach and prevents its absorption.

I'd space it a bit anyway, because we don't know if magnesium in the blood serum would affect the drug too. There is such a larger volume in the blood than the stomach, so I think both would be diluted out quite a bit. Much of the magnesium in the lotion would stay around the area it was applied to. But I do know it does get into the general circulation, because it lowers my blood pressure quite a bit. (more so when applied to my arms than my legs and feet).
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heb1212 (08-27-2015)