I had a triple phase bone scan on my feet a few weeks ago, and the results came back normal with no indication of CRPS. I know that this doesn’t mean that I don’t have CRPS, and from what my doctor says this means I am past the point that it would show increased uptake because this is seen usually early in the disease. I have been emailing with a doctor in Italy because I have been considering going there for neridronate. He said that with my bone scan results, the drug would not be able to taken up and I would see very little or no benefit. Both my doctor and the Italian doctor were surprised that after 10 months of my CRPS duration I would already have a normal triple phase bone scan. My question is, has anyone discussed bisphosphonate treatment with their doctors, and is that the consensus that they won’t work unless your bone scan showed increased uptake of the tracer in the affected site? Has anyone done bisphosphonate treatments with a normal bone scan and had them work? I am confused because the US trial for neridronate is taking anyone regardless of their bone scan results or disease duration. It seems to me there are a lot of people for which this type of drug won’t work. Thanks