I used it for a very short time when I was being bounced from one dr to the next. My meds were not well managed...drs started and stopped me abruptly and shortly after starting savella I was diagnosed with serotonin syndrome caused by the meds. This had been causing a variety of odd symptoms which went undiagnosed because my RSD was getting worse and spreading and those symptoms complicated everything makin. it hard for the drs to diagnose what was going on. For me...at its best the savella did nothing and at its worst it contributed to the serotonin syndrome. Not a usual case though or fair assessment though given all the other stuff that was going on at the time and too many drs starting and stopping meds abruptly. I was in such bad shape...I look back now and wonder why I let them do that...but at the time my pain was at a constant 10, spreading, and I thought I was losing my mind...and I probably was a little.