Sinemet has worked well for my tremor. I can sometimes feel when I am "under" dopamine"d". Having said that Sinemet doesn't work the greatest for my symptoms and I went all the way up to 7 pills a day (currently 2-3) . The symptoms include sleeping issues, constipation, depression, anxiety, apathy, pain, rigidity. The cannabis works well for all minus the constipation.

Along with the cannabis, I do bike 4 times a week (15-20 miles per) at a pretty good clip. I recently started the GAPS diet and finally have had a breakthrough on constipation.

A little at a time but I feel so much better than 6 months ago and 12 months ago. I attribute changes to my three part approach (gut, exercise, natural meds) but things were very noticeably better with cannabis.