Comeonthen,

In regards to the amount of lesions for someone in their 40's...I am currently 49. In 2007, I was 41 and my MRI revealed 2 lesions. In 2014, I was 48 and my MRI revealed 20+ lesions. I am an ex-smoker. I presented and still have symptoms that are found MS. My Neuro ran the complete gamut of tests including the LP. Everything was negative for MS. My PCP then decided I had Fibro. My Neuro even sent me to the MS specialist in Jacksonville, FL for a second opinion. My Neuro continues to follow me every 6 months (he treats my migraines) and does an annual MRI to compare to the previous MRI's. This year's MRI was unusable since my Rheumy had me on gabapentin and it caused me to jerk and there was too much motion on the MRI.

There are many reasons you could have lesions on your brain. My 23 yr old daughter has 3. Migraines can cause them, ischemic episodes, etc. I would suggest to you that you not focus so much on the lesions, but to focus on the symptoms and work with your doctors to find answers from there. I am currently in physical therapy for muscle imflammation and strengthening and my diagnosis is ONLY Fibromyalgia.