I also just started the Lyrica a little over a week ago and I keep wondering when it is going to start working. So far I don't feel any effects at all - good or bad. In fact, the pain feels a lot worse. I am thinking about stopping it. Had a couple of really bad sleepless nights from the pain. I also tried the Cymbalta before this and had a really bad reaction to it, but the Lyrica does not seem to be doing anything.