I also have developed muscle twitching in the last month or so in my legs. The neuropathy seems like it is getting a lot worse. It used to be just my feet, now I have stabbing in my ankles and the pain is halfway up my calves. My muscles have started twitching and my calves feel like they are cramping. I take magnesium citrate. The pain has gotten so bad that I can't sleep at night. Also started new weird sensations like water dripping up my legs.