My daughter-in-law is full Japanese, born and raised just outside the Kobe main metropolitan area. She and my older son met while both were in their Doctoral programs at Purdue U. Her main project was spearheading research on a noise-reduction systemic problem for Samsung, under whose grant she drew some of her financial compensation not to mention Doctoral credit.
Corporate dinners Eri was obligated to attend usually included a ceremonial toast at some point in which she was obligated by corporate manners and protocol to participate. Without fail, one mere sip would make her deathly ill, sometimes for days.
She managed to educate Jordy into a Sake quasi-connoisseur through her cultural second-hand knowledge, while never partaking herself, seeming possibly victim of that particular genetic chemistry.