hi julie. i hope you're feeling better today and that you treatments are helping manage your pain. i have never done ketamine and am not a dr but have learned that if i have questions about my drs procedures i ask them now. don't be afraid to ask you dr what he is doing. imo, it's ok and your right as the patient to know what is going on. if i were you i would just ask kindly and calmly what your dr is doing and why he is increasing your dosage. a good dr will explain what he is doing. i hope that the ketamine and cream help you to feel better soon. take care.