Originally Posted by Arsene

Harry, Thanks for your input on Mirtazapine use for PD tremor.
I recently tried this starting with one half of a 15mg Miratazapine tablet.
It certainly reduced the strong tremors from day one.
The downside for me was that I became "drugged" for the following day to the extent that my wife advised I looked stoned all day and became withdrawn and vacant. I reduced my Mirtazapine intake to a quarter of a 15mg tablet per night and still slept for 12 hours and felt stoned the day after.
It appears that I am sensitive to most meds but this Mirtazapine really knocks me over. However it is the only med that has reduced my intense shaking so I will continue with caution. Also the Mirtazapine has improved my mood.
My regular meds are Sinemet Plus at 4 per day and Mirapexin 0.018 at 4 per day. I am 64 with PD for 4 years.
Arsene