Agreed - not optimistic that copper IV will change the picture much but to your point it is lower risk and we will likely know if hematologically it improves the neutropenia at least. Also, in general, I am learning there is very little research related to copper and copper deficiency. As a result, not many doctors have a grasp on what its function is and what the consequences of having a persistently low level over a long period of time could have led to. All that said, the autoimmune process is a more likely cause of this in my opinion or perhaps they are all inter-related. Who knows?