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Old 11-08-2015, 09:33 AM
glenntaj glenntaj is offline
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Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default Welcome to Neurotalk--

--though I feel badly that is it neuropathy symptoms that have brought you here.

What you describe does sound like an acute/sub-acute neuropathy episode, and those often do improve with time, though the improvement may be patchy and incomplete. Unfortunately, with those type of neuropathies, which are often autoimmune or toxic in nature--and you should be getting testing for antibodies to peripheral nerves as well as potential toxicities (and you, obviously, would be the only one who could speculate as to what you might have been exposed)--it's very hard to predict prognosis.

While EMG/nerve conduction studies are generally indicated for any peripheral neuropathy, those that are predominantly small-fiber in nature (involving the thinly myelinated or unmyelinated fibers that subsume the sensations of pain and temperature, as compared to myelinated fibers that transmit mechanical touch, vibration, position, and motor functions) often show up as "normal" on these tests as they are not precise enough to localize small-fiber dysfunction--that often takes much more specialized testing up to and including skin biopsy to quantify intraepidermal nerve fiber density. Most of your symptoms so far seem to be small-fiber in nature.

One thing that is concerning is that B12 level--B12 deficiency can present this way (and often with subacute degeneration in the spinal cord as well). B12 supplementation is definitely encouraged. Sublingual wouldn't make much of a difference if you megadose to allow enough B12 to be passively absorbed--at least 1000-5000mcg/day to allow a 1-2% passive absorption rate and build up stores--and preferably a methylcobalamin source if you are one of those people who might have a methylation chemistry mutation that would cause difficulties converting the more commonly available cyanocobalamin (and nobody needs cyanide radicals running around the body anyway).

You should look at both our peripheral neuropathy section here:

http://neurotalk.psychcentral.com/forum20.html

And we have a distinct and very comprehensive B12 section:

http://neurotalk.psychcentral.com/thread85103.html

Last edited by glenntaj; 11-09-2015 at 06:47 AM.
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