Sorry I have not been posting lately. I was quite suprised to see this thread come alive again. Vintagewine, thanks for the kind words. I have recently found another PM doc that is a more willing to try different medications. Bio, he started me on LDN!!! I have it compounded at a local pharmacy. It's been about 3 weeks now at a 2mg dose. No side effects. It seems to be calming the burning nerve pain. It does not do much for the crunching bone pain, but less pain of any kind is certainly welcome. I agree Bio, I wish more people were offered the opportunity to try it, with a doctors help. I fought for months for this. I am hoping for continued improvement over time. ~mama mac