I can't offer a lot of advice beyond just telling your wife that she has a lot of company with non-standard symptoms. I have weird sensations all over that do indeed seem to move around. I call them "rushes" as they're like that "chill up and down your spine" feeling when you get a shot of adrenaline, only they occur in isolated areas.

It's easier said than done I know, but getting the anxiety and worry under control will help tremendously. My symptoms improved a lot once I just became more accepting of my situation and adopted an "It is what it is" mentality. It doesn't mean I've given up on the fight to get better, I just know it's not going to dibilitate me or kill me. I only have occasional bad nerve pain now. Whether that's due to dietary changes, supplements, an attitude change or just a change in pathology, I don't know.