Thread: B12 and Folate
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Old 11-25-2015, 05:44 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

If one has the DNA mutation, called, MTHFR, then the use of BOTH methylfolate and methycobalamin is necessary.

If one does not have this mutation, then the folate is not as necessary. The American diet has many fortified foods, with folic acid in them. The MTHFR mutation cannot methylate (activate) folic acid properly.

Commonly when people have B12 testing, the folate measured then is usually high. This is called the methyl trap. This happens when B12 tests low.

Products with methylfolate are a bit more expensive than methylB12 products. One such is called Metafolin by Solgar.
But there are others, now too.

I wouldn't go over 800mcg a day.

The testing for MTHFR can be done thru 23andme.
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"Thanks for this!" says:
zkrp01 (11-26-2015)