Thanks, Ragtop. Much appreciated. So perhaps I should get this checked out. I'll check out Promethease. I would have to go through 23andme and get all the raw data first, right? So that would give me all the information I'm not too keen on knowing, correct? I would then get even more info not just methylation info from Promethease? I suppose I'm just confused about the process.
Now, could I just supplement with sufficient B6, folate and B12? Or does it help to get even more precise in respect of dosage based on such info?
I should note, also as an FYI for MrsD, that my B12 came back as 515.
Quote:
Originally Posted by Ragtop262
David:
For info - 23andme originally gave out full genetic reports, then they were prohibited from doing so by the government. Now, in the past month or so they were allowed to provide genetic reports again, but they only provide information on a handful of conditions which do not include MTHFR.
However, there are several companies that will take the "raw data" from 23andme, and run a very detailed analysis. (I used promethease) There are also some others that will do a specific analysis on your potential methylation issues and MTHFR. Note that 23andme/promethease has several genetic markers (such as the "alzheimers gene") that they will not provide reports on unless you specifically "opt in".
I understand your concerns over privacy, and not wanting to know "too much". I had the same concerns, but decided that knowing my MTHFR status was more important than my privacy concerns. Based on the testing, I found that I have the C677T mutation as well as several other methylation related mutations. As a result, I've been able to tailor my supplement regime to deal with those issues. My SFN symptoms haven't gone away, but they haven't really progressed since improving my supplements. And, I definitely "feel better" overall.
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