Quote:
Originally Posted by DavidHC
Thanks, Ragtop. Much appreciated. So perhaps I should get this checked out. I'll check out Promethease. I would have to go through 23andme and get all the raw data first, right? So that would give me all the information I'm not too keen on knowing, correct? I would then get even more info not just methylation info from Promethease? I suppose I'm just confused about the process.
Now, could I just supplement with sufficient B6, folate and B12? Or does it help to get even more precise in respect of dosage based on such info?
I should note, also as an FYI for MrsD, that my B12 came back as 515.
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Had you been taking vitamins when you had that test?
If not, it is still rather low. You would do better to have a level of 1000 or so. If you had not taken any B12 for several days, it is still just barely normal. As a first test, you really do not know if you are coming down, or going up. If you are coming down with that 515 that would be concerning.
People with homozygous genes (meaning only one of two genes in a pair) tend to limp along with it until something happens to stress them, or they use up all their liver stored B12...and then symptoms appear. The heterozygous ones with 2 genes missing often develop symptoms at younger ages.
Certainly you can supplement yourself:
50mg P5P (B6) -- NOW makes an affordable one.
400-800mcg of methylfolate (Metafolin)
1 to 5mg methylcobalamin a day (on an empty stomach).
None of these is problematic in any way.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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