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Originally Posted by DavidHC
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HI David,
MK7 is definitely more bioavailable, but I've been putting in a little bit of research and it seems like the clinical properties in the MK7 are NOT as proven in the scientific literature as they are for MK4. Part of this could be because MK7 has been studied less than MK4. And there have been no comparator studies that have looked at which one is superior...at least I haven't found any yet.
In rat studies they have looked at arterial calcification and found that K2 MK4 is what the arteries prefer. We aren't good converters of K1 (leafy greens) to K2 MK4, so supplementing with the MK4 form will possibly help reverse or prevent arterial calcification.
http://www.ncbi.nlm.nih.gov/pubmed/17138823
MK4 seems to be very effective at preventing osteoporosis related fractures in humans.
http://archinte.jamanetwork.com/arti...ticleid=410550
This study on MK7 concluded that it did not stop bone loss.
http://www.ncbi.nlm.nih.gov/pubmed/19937427
My list of pros/cons for K2 MK4 vs K2 MK7:
- MK4 is synthetic and while MK7 is natural
- MK7 is more bioavailable than MK4
- MK4 is more studied and proven than MK7
- If you have a soy allergy, you could react to MK7
Would you agree with this? Has anyone looked into this and what do you think? I'm probably going to stick with MK4 for now, but I'm always open to new information.