I've been working with Oil of Oregano (like Now Foods brand) and liking my results more and more for pains and a dental issue. I add OOO to all of my topicals to give them an extra umph. I even use vaseline and add OOO drops and tea tree oil drops and some drops of DMSO. Vicks salve too. Getting ready to buy a new supply of Topricin, it worked great in the beginning over a year ago but in my case joints just worsening so it takes more to keep going.