So happy to read informed replies on B12 deficiency. I have only been treated for around 2 weeks. Have pretty severe polyneuropathy (missed by two docs because my serum level b12 is "normal"). Started with Cobalamin for first 10 days, but luckily was able to get methyl in syringes and am on my 3rd dose.

I want to do everything I can do minimize permanent nerve damage in my legs and feet (which are 100% numb!). Have had mild symptoms for over ten years caused by reflux med.

Question: I am taking Nuerontin (3x per day @300mg) to manage pain and muscle spasms (and, so that I can sleep at night). Would an anti-seizure med like this interfere with effectiveness of the b12 methyl injections?