Hi, I'm new here.

I've been suffering from Bipolar Disorder (with only very mild Mania) since 1996.
I have been hospitalized four times since then and just have been hit with my third major depressive episode that leaves me in bed on many days, unable to function. I can't feel anything like joy at the moment and lost interest in everything I used to enjoy which is to me the worst symptom of all.

On some days I function well enough that I can attend an outpatient program during the day. What keeps me from being hospitalized are the very terrible conditions in the psychiatric wards in this area.


I had been on Cymbalta + Lamictal and Seroquel for over five years and these meds had helped me with my second major depressive episode. These meds were working for a a good while and then after years they just stopped working.

Last year I started to get so depressed again that it came to the point where I felt suicidal. I had attempted suicide twice before out of impulsive uncontrolled emotions. BUT I actually want to live and survive this episode too.

Over two months ago they took me off those meds that had stopped working and put me on Wellbutrin and Latuda - without any success... the depression, fatigue and emotional numbness are still here.
Now they added Effexor and I'm now taking this following combination: 150 mg Wellbutrin + 150 mg Effexor in the morning, and 120 mg Latuda at night.

It's been 10 days with the Effexor and nothing has changed. I was told it can take up to 6 weeks to feel any effects. I'm not sure how I will make it there, but I somehow have to make it through. I'm hoping to find some support here.

Thanks so much for listening and blessings to all.