--small fiber neuropathy will NOT result in muscle wasting/weakness; in fact, since small fibers subsume the sensations of pain, temperature and autonomic functions, and not motor functions, one of the distinguishing characteristics of small fiber syndromes is lack of motor symptoms.

That having been said, many of the conditions that can result in small fiber syndromes can have effects on muscle as well, but in those both the small fiber and muscle problems are secondary to the condition (i.e., diabetic amytrophy and neuropathy, mitochondrial syndromes).

And, the very fact of the symptoms can lead to people wanting to move less, be less active, and to be more fatigued more easily. That lack of use is more likely to result in muscle atrophy than the neuropathy itself.

AND--there are neuropathies that are primarily small-fiber with some large fiber component, in which deterioration of motor nerves can result in muscle weakness and wasting.