Thanks Ron.

I'll update the app to include Sinemet CR as soon as I can find some consistent data. Angela as been so kind as to forward to me some papers on the subject.

I take your point that rasagiline and levodopa are different. But, they are both involved in the same battle: increasing dopamine levels in the brain. Levodopa leads to dopamine being created and rasagiline reduces the amount of dopamine that is lost. Either route can lead to the same amount of dopamine being present in the brain. If you could go on adding to the rasagiline dose and get increasing levels of dopamine preserved it would be a wonder drug. Unfortunately, it does not give better results for doses above 1mg/day - presumably it has done its job as a MAO-B inhibitor and there is no more MAO-B to inhibit.

John