Kiwi, I am so glad you asked. I learned about this second hand from my cousin. His wife explained that the B Synergy had to be taken with the biotin for balance. I assumed that it was correct because I have heard this from other sources. I called the pharmacy to get more details. Both the neuro and the pharmacist believe that other b's in high, mgs- dose, are necessary for the balance of the b metabolism. It guards against any of them being insufficient or deficient as well. The pharmacist explained that the standards of dosing are too low, especially for someone with ms. As far as the b's in concert he didn't really give me any more specifics, even when I pressed him for more detail. He did say that there was no charge for the b synergy which means that the biotin alone will run $100.00 with or without it for what it's worth. He genuinely seemed to just want a good outcome and believed in the addition of the B Synergy, which is a proprietary blend.
I don't know, what do you think?