Quote:
Originally Posted by glenntaj
The gold standard for celiac testing is an intestinal biopsy with at least a half dozen villious samples taken from various locations. But one can get a celiac serologic panel done to see if anything shows up there. This consists of measurements of anti-gliadin IgG (the most sensitive but least specific indicator of gluten problems), anti-gliadin IgA, anti-tranglutaminase IgA (the most specifically associated with villious damage) and total IgA (because congentially low levels of this can skew the other tests).
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What might be the meaning of positive Gliadin IgG AB, when the rest of the tests are negative (Gliadin IgA Ab, IgA isotype of tTG, T.TRANSGLUTAMINASE, Deamidated Gliadin Peptide Ab) ?
I was tested because my sister was diagnosed with celiac, although I didn't have any GI issues, just very low B12.