Yes, there are three general types, I believe: primary, secondary (both of which are not hereditary) and familial. I don't know about your last question, perhaps someone more knowledgeable than I can offer information, but I can say that urine tests are not accurate for diagnosing amyloidosis. The most accurate test that's minimally invasive but quite accurate, upwards of 90%, is a fat pad biopsy. This can detect amyloid deposits. The most accurate is to biopsy the organ tissue itself, if a particular organ, say the kidney, is suspected, but that's obviously much more invasive. I hope this helps.
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Originally Posted by MAT52
I am not too knowledgeable about this but aren't there other non hereditary forms of Amyloidosis? Owing to a frequently high total protein in full blood count and a widespread small fibre neuropathy and history of Rheumatoid - my rheumatologist requested a Bence Jones urine test to check for Amyloidosis or Multiple Myeloma. I got a bit freaked out when I found out what he was looking for but had a phone call late on Christmas Eve saying it was negative. Hugely relieved but have been wondering what is making my protein high, also evidenced by paired oligloclonal bands in my spinal fluid and serum blood.
Do you happen to know whether it's still possible to have Amyloidosis or MM with a negative Bence Jones?
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