newbie,
Were you given nasal spray antibiotics ? I did not know they could be applied that way. Nasal steroid sprays are not uncommon but help with some and make others worse. The following article explains this.
Here is an article about a study done about treating sinus headaches. .
http://www.webmd.com/allergies/antibiotics
There should not be much interaction to worry about. Stay strong with brain healthy nutrition and supplementation because illness can make PCS worse by stressing the brain.