Deepak2016, 25 mg/day thiamine is well above the RDA, which is about 1 mg/day. It seems that an intake of a lot of thiamine is probably safe - probably it is not absorbed well at intake levels above about 5 mg/day - the excess is just excreted. Because of this a Tolerable Upper Intake Level (UL) has not been set for it though that does not rule out the possibility that it could have adverse effects in some people (taken from the link that I posted above).

Biotin deficiency is very rare (people whose diet is adequate get enough from their food) but taking a pill containing it will probably not harm you.