went back thru my notes, saw that i tried 25/100 + 50/200 + 200MG ENTACAPONE one time and got at least 3hrs, my notes said i was still on after 3 hrs but haven't tried it again. mentioned this to my neuro and he wanted me to not deviate from the plan, get the best dose of 25/100 + ENTACAPONE and then deviate from that.