I have lupus and Sj. Syndrome.

I take a b complex and a separate low dose of b6 with no issues that I'm aware of. You don't think your high b6 levels are related to autoimmune symptoms? I do recall reading that having a very high level of this is not good for you.

I have dry eyes and mouth. Common for lupus and very common with Sj. syndrome.
I take Ubiquinal. This seems to have helped with that...especially dry mouth. I use preservative free eye drops daily and this is also of great help.

http://www.ncbi.nlm.nih.gov/pubmed/21406193