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Old 02-24-2016, 12:36 PM
DavidHC DavidHC is offline
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Join Date: Nov 2015
Posts: 732
8 yr Member
DavidHC DavidHC is offline
Member
 
Join Date: Nov 2015
Posts: 732
8 yr Member
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Ragtop,

I'm sorry to hear that your gut issues are acting up again. It's not fun, I know too well. Have you considered SIBO as the root cause? There is leaky gut that's certainly related, and we now see vitamin D plays a role in that it seems. I'm trying to get to the root of mine too, or to try to heal it. I do think it's due to my intestinal permeability that my SFN and other health problems arose...that's my best guess anyway, and it seems like a good one. Anyway, I hope you improve.

I also wanted to thank you for posting about your mutation in the VDR taq gene. I didn't know about this. What does it mean for you? Perhaps it's worth getting myself checked out? I don't think I have difficulty creating D from sunlight, but I could be wrong, since my first ever D serum test was this past November. But I suppose I would have had problems earlier than in my 30s, if I had issues with vitamin D. Perhaps not though, and if vitamin D is connected to the gut, considering I've had those issues for many years, perhaps there is a problem with my ability to produce vitamin D. I'll have to look more into this. Thank you for pointing me to it. I had no idea.

Well, it's frustrating and annoying and all that, true. I also hear you about the need to make medical and health research a second job. It's taking up so much of my time, and I find myself reading more medical literature than my own work. At some point I'll have to slow down. Hopefully you can find a solution to your issue.



Quote:
Originally Posted by Ragtop262 View Post
Thanks for the links guys. Genetic testing shows that I have a mutation in the VDR taq gene. And I have suffered with IBS for most of my life. Probably time for me to look at this issue again.

The problem with genetic testing and looking at all the methylation related mutations you can have is that there are so many positive and negative interactions between the various mutations. So, if you have multiple mutations like I do, its hard to know what to do. The specific dietary supplementation necessary to "fix" one issue might be contraindicated for one of the other issues.

My issues had kind of settled down for a while, but are acting up a bit again. I was taking a bit of a break from making health research my second job. But, I think its time to try and re-examine my approach to managing my health. But it does get depressing when you find so many potential problems but so few potential solutions.
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