I've never heard of too much mestinon as being 'toxic'. I take 60mg q 2 hrs (waking hrs) and that's because I'm in a relapse right now, well, the last 4 yrs. Before that, I was on 60mg q 5-6 hrs. I started on prednisone in 2001 but only because I was having breathing problems. I desperately want to get off the stuff. CellCept didn't do the trick for me and now I'm hoping that I'm a candidate for the immune reboot procedure at Johns Hopkins. I'd suggest to your neuro about trying CellCept or Imuran before going prednisone.

Jennifer in Ontario