This article may be of interest to the NT community; http://www.sciencemag.org/news/2016/...&et_cid=332196

An explanatory comment; "good cholesterol" (HDL) is generally protective against cardiovascular disease because it delivers excess cholesterol to the liver (a process called reverse cholesterol transport) - the liver then disposes of it.

SR-BI (referred to in the link) is a scavenger receptor, expressed on liver cells - its job is to allow HDL to dock to those cells, allowing them to take up cholesterol and dispose of it. If SR-BI is absent or defective, this process does not work well.