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Old 03-15-2016, 06:12 AM
glenntaj glenntaj is offline
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Join Date: Aug 2006
Location: Queens, NY
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glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default Many autoimmune neuropathies are inflammatory--

--but not all, as it depends on what pathways and mechanisms the autoimmune attack is taking.

There are plenty of autoimmune attacks on nerves with autoantibodies specific to components of peripheral nerve in which the usual inflammatory markers can be quite within the normal range, as the autoimmune attack is quite specific to those components and usually has few, if any, more systemic effects (although obviously damage to nerve has widespread consequences to one's functionality). These can be contrasted to the more global autoimmune attacks associated with such conditions as the anti-nuclear antibody associated vasculopathies and connective tissue disorders (i.e., lupus, polyarteritis, scleroderma) in which the neuropathy is secondary to the autoimmune attack, often through cross-reactivity.
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