When I was in my mid 30's and living in Southern California, I had terrific migraines, especially when the Santa Ana winds blew. My internist also taught at UCLA and he said they were experimenting with B12 shots for migraine sufferers and so I began getting a shot every month. I responded very well, and never had the ocular symptoms that accompanied the migraine as long as I got that shot.

This was before we had methocobalamin but the B-12 shots really did help me. My doctor said they did not help very many people at UCLA, however, my headaches were few and far between and no more visual disturbances.

Now I'm retired, no longer have migraines, but do have PN since 1999 -- and now I take the methocobalamin daily for that! I think there's a connection but am not sure what it is.