I took Methotrexate in the past for awhile, but not for MG. I also have rheumatoid arthritis, so I took it for that. This may not be a particularly helpful post, but I see you have had no responses thus far.

The main thing I can tell you is to be sure to follow up on any blood tests that your doctor recommends that you should do. Everyone is different, but I was not able to tolerate Methotrexate over the long-term due to problems with liver function. Many people tolerate it just fine, but it's important to check your liver function with blood tests regularly.

I hope you'll do well with it, and it will be helpful for you. I send lots of good wishes your way!

Take care,
Erin