Snoel, This is a bit aside, but with that kind of antacid use, you need your B12 levels checked. You can't digest your food well enough to obtain B12 from your food with so much antacids. It can also reduce albumin, iron, calcium, etc.

Baddad, As far as to much Mestinon, most research says to keep dosing at 90 - 110 mg at a time. Too much will flood the neuromuscular junction with acetylcholine and can lead to a cholinergic crisis. It's very similar to a myasthenic crisis, so patients might think they need even more when what they need is less. BUT talk to your neuro first before making changes!

Annie