Originally Posted by AnnieB3

Snoel, No, it's not an adverse reaction to Mestinon. Trigger finger is caused by an inflammatory process, which itself has many causes.

Frequency in Mestinon dosing, with a smaller dose (90 - 110 mg), is often a better way to go. Instead of every 4 hours, every 2-1/2 to 3 hours is common. But, of course, talk to your neuro first before making any changes.

You're basically flooding your neuromuscular junction with too much acetylcholine. I'm surprised you haven't had a cholinergic crisis by now.

Annie