I am diagnosed with something in the autoimmune connective tissue family. I have a high speckled ANA, small fiber neuropathy, and my lip biopsy was borderline. One neurologist thinks Sjogrens, and my rheumatologist agrees that plaquenil would be worth a try. The one problem I don't have, however, is swelling joints which from what I understand the plaquenil is most helpful for, so I haven't tried it yet. I do have terrribly dry eyes, but I can't figure out if its from autonomic nerve damage (which I have), or sicca.
No one will try me with IVIG either. I had one local neuro who attempted the process, but said my insurance wouldn't allow with out more positive tests.