I have a hard time anytime there is a big shift in weather...so usually the period as seasons transition. Winter and summer are strange seasons for me in that I do better in the warmer weather of summer...but some places have the air conditioning so high that it puts me into a bad flare up. Winter...the weather outside is difficult for me but inside it's always toasty warm so I am more comfortable once I am inside a place. Spring and fall tend to have more weather changes...which is rough...but then again the temps inside and outside tend to be more even keel so that's better in that sense.