Everyone is different. B6, has to be activated in the body as Pyroidoxine itself is not biologically active in the tissues. This conversion is dependent on B2 (riboflavin) and other biological factors, which can vary from person to person.
Deficiency as well as long term toxicity of high dose supplements both give clinical neurological signs so diagnosis is difficult. Even the testing may be faulty, so that furthers poor diagnostic accuracy.
Here is a good monograph about B6:
Dietary Supplement Fact Sheet: Vitamin B6 — Health Professional Fact Sheet
I think others here could benefit from some data, links that show the dosing in studies that becomes problematic. Anecdotal comments from patients, is not that helpful in the long run, IMO.
Quote:
Originally Posted by LisaAnnB
I am so tired of seeing a new person everyday on the b6 boards who has been poisoned by their doctors with the advice of supplementation of b6. It is a toxic vitamin. Some can take it and don't get nervous system
Abnormalities, but many many do! Even small amounts of b6 can be toxic. It is not normal to have elevated b6 levels when supplementing. It means you are toxic. This stupid vitamin keeps ruining lives on a daily basis and I don't understand why the word has not gotten out about it. Some become toxic within days, weeks, months of taking it. It will cause PN in many people, a severe PN. People, please check your supplements. This is one not to mess with unless proven to have a severe deficiency. Eat an avocado.
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Weezie looking at petunias 8.25.2017
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