Thread: Pharmacology of mucuna pruriens
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Old 06-19-2016, 08:12 AM
johnt johnt is offline
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johnt johnt is offline
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Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
Default Pharmacology of mucuna pruriens
A recent paper by Cassani et al. [1] has a lot of interesting information on mucuna pruriens (MP). Highlights:

- median levodopa concentration in dried mucuna seeds was 5.29%

- given the lack of a DDCI (e.g carbidopa) in MP, for a given amount of levodopa, the area under the curve of plasma levels against time is 3.5 times higher for C/L than for MP.

Reference

[1] "Mucuna pruriens for Parkinson's disease: Low-cost preparation method, laboratory measures and pharmacokinetics profile"
Erica Cassani et al.
Journal of the Neurological Sciences, June 15, 2016
http://www.jns-journal.com/article/S...183-6/fulltext

John
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