There have never been any reports of SSRI/SNRI's helping with cognition. Amantadine has helped on rare occasions. ADD/ADHD meds help some but their use is controversial.

Some people just have to learn to live with persistent PCS. I've lived with it for 50 years at increasing levels after additional bumps and aging.

I don't know if you were around for the update on sleep and PCS. Last Feb, a neurotrauma sleep specialist spoke at our TBI Support group. She said that amount of sleep does not matter as much as getting full cycle sleep. REM sleep is where the brain repairs (neurogenesis) but slow wave sleep is most important as it is when the brain flushes toxins.

I need to be able to get in bed without any thoughts from the day.

For me, getting my sleep figured out did the most at minimizing my symptoms.

A sleep study may help you figure out if you are getting full cycle (all of the stages) sleep.