Thread: Blocking key enzyme may halt PD symptoms and support use of Nilotinib
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Old 06-28-2016, 08:38 AM
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Join Date: Nov 2011
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Originally Posted by engsec View Post
I think above study about effects of "Nilotinib" for PD, could confirm the effects of anti-malaria drug (chloroquine) in PD. Or both could confirm together . but the key is that "chloroquine" is more cheaper drug.

This study shows that chloroquine is acting as an Tyrosine kinase inhibitor in malaria diseas:
Inhibition of a protein tyrosine kinase activity in Plasmodium falciparum by chloroquine.
Inhibition of a protein tyrosine kinase activity in Plasmodium falciparum by chloroquine. - PubMed - NCBI

In other hand , researches shows that antimalarial drug "chloroquine" has good effects on PD.
Anti-Malaria Drugs May Hold Promise as Parkinson’s Treatments
- Jul 23 2015
Anti-Malaria Drugs May Hold Promise as Parkinson’s Treatments - Parkinson's Disease Foundation (PDF)

Best Wishes
All the soldiers who went to Viet Nam took a weekly dose of 500 mg of chloroquine phosphate for malaria prophylaxis. This would have been for at least a year.
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"Thanks for this!" says:
engsec (06-29-2016)