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Old 06-30-2016, 05:40 PM
MAT52 MAT52 is offline
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Join Date: Feb 2015
Location: Scotland, UK
Posts: 529
8 yr Member
MAT52 MAT52 is offline
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Join Date: Feb 2015
Location: Scotland, UK
Posts: 529
8 yr Member
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Quote:
Originally Posted by kiwi33 View Post
An elevated anti-nuclear antibody (ANA) titre is suggestive but not necessarily diagnostic of a number of autoimmune diseases. False positives (an elevated titre with no disease) can happen.

Often a titre measurement is followed up by looking at the visual pattern (homogeneous, speckled, etc) of ANA staining in cell nuclei.

This information might help you http://www.racgp.org.au/afp/2013/oct...antibody-test/.
Thanks Kiwi- I only have as much information as I've posted here about my ANA - no breakdown yet.

I'm assuming that it is very significant in my case, given that I've been told by my previous rheumatologists that I can't have a connective tissue disease without it - despite raised inflammatory markers, paired o bands and many symptoms corresponding with connective tissue diseases. Also I have never understood how it is possible that we allow RA to be clinically diagnosed and treated in seronegative form - but not the others? I suspect this is because synovitis and RA erosion show up clearly in imaging so can't be refuted - unlike diseases such as Lupus or Sjogrens which can be much harder to confirm without the autoantibodies.
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Sjögren’s, Hashimoto’s and Systemic Sclerosis with Raynaud’s, Erythromelagia and small fibre polyneuropathy, GI problems top to tail, degenerative disc disease and possible additional autoimmune diseases
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"Thanks for this!" says:
ElaineD (07-20-2016)