A number of the symptoms noted here along with a reduced tolerance for exercise can signal amyloidosis or at least make it worthwhile. It might be worth looking at the symptoms and seeing if it's worth exploring with your physician. I have a team looking into it for me. Almost always it's a quickly degenerating illness, so if, say, you've had symptoms for years and/or the progression is rather slow, then you likely don't have amyloidosis, but there are some genetic types that can degenerate more slowly than acquired types, say the TTR, or so my team of physicians have said.