Quote:
Originally Posted by mskari85
I am hoping somebody can explain HOW an autoimmune disease causes peripheral neuropathy?
I was recently diagnosed with rheumatoid arthritis by a positive rheumatoid factor and a positive anti-ccp. My ANA was negative and all other autoimmune tests were negative.
I have scoured the internet and this forum and I still do not understand how the two are connected? Is my immune system literally attacking my nerves? Is the inflammation causing the PN?
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Can anyone explain the relationship between autoimmunity and inflammation? I have SFN and "the antibody profile of a lupus patient" and am followed by a rheumie as well as neuro, but have no signs of inflammation in blood work, skin biopsy, or muscle biopsy. My CRP and sed rate are always at the low end of normal. Nothing but my ANA, anti-dsDna, and anti-Ro come up positive. Everything I read about autoimmune conditions seems to assume that there is inflammation.